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申请/专利权人：复旦大学

摘要：本发明属于司法鉴定分子遗传学应用研究领域，具体涉及一种用于亲子鉴定的SNP位点组合、及其检测引物对和应用。该SNP位点组合包括520个SNP位点，基于该SNP位点组合，所选的位点在群体中均符合Hardy‑Weinberg平衡经过Bonferroni校正，各位点不连锁，并处于连锁平衡状态；选择位点时参考了不同数据库、相关文献并结合法医学中广泛使用的遗传标记，可获得更多的遗传信息及更高的法医学效能；有利于进行疑难生物检材个体识别与孕妇外周血产前亲子鉴定等法医学应用。

主权项：1.一种用于亲子鉴定的SNP位点组合，其特征在于，包括520个SNP位点：rs868163、rs3007429、rs3007430、rs2076605、rs7531163、rs607254、rs2361660、rs7516939、rs494198、rs6588052、rs11208265、rs472908、rs3736296、rs2274570、rs3811003、rs9428083、rs9427094、rs703116、rs1920149、rs7536561、rs647347、rs2274064、rs12042179、rs4844573、rs2076355、rs12031285、rs630120、rs12042900、rs7527925、rs11578981、rs7552783、rs2045955、rs2618702、rs2805396、rs1332777、rs10802626、rs2256242、rs10927011、rs2280132、rs2271621、rs7561070、rs4072407、rs455060、rs3738984、rs3771274、rs2020911、rs2276625、rs2244182、rs2271244、rs72481904、rs1061305、rs16830136、rs2288201、rs12620077、rs1867864、rs1542484、rs830973、rs12613075、rs2366751、rs2303838、rs2042995、rs2562839、rs12997453、rs3024866、rs1208081、rs2242074、rs17552879、rs3213784、rs6704780、rs12991025、rs34490902、rs2304774、rs17868324、rs1105879、rs4234097、rs6756901、rs456168、rs2733532、rs3729587、rs3816526、rs2507940、rs13097628、rs7641844、rs1799987、rs936175、rs13066214、rs749512、rs6445873、rs4681982、rs2290174、rs533852、rs1463138、rs2713604、rs1683787、rs2681092、rs16861582、rs2303909、rs9290259、rs1515442、rs2593813、rs2028572、rs9851685、rs2286342、rs899691、rs2306400、rs13121363、rs13144326、rs7655165、rs12650452、rs2125314、rs225170、rs6856362、rs7660664、rs34840208、rs7677541、rs227365、rs17009761、rs62333013、rs2166337、rs4429853、rs13170062、rs162850、rs7710284、rs6451206、rs11957963、rs476569、rs1801033、rs706714、rs182190、rs309557、rs4916683、rs274557、rs2303068、rs4072924、rs438464、rs2236277、rs2842949、rs2071303、rs3737095、rs3818554、rs167772、rs3920621、rs10948667、rs9474140、rs9367689、rs4712138、rs2230862、rs4710457、rs1936439、rs2305837、rs519068、rs1875845、rs9448893、rs3828753、rs3734353、rs6922753、rs2273752、rs7754205、rs3813328、rs902373、rs3798663、rs6914831、rs3762000、rs22908、rs6904364、rs3818110、rs9371581、rs9383985、rs9397102、rs1873176、rs214968、rs3734440、rs9356399、rs4716346、rs2527509、rs852423、rs6461252、rs7782939、rs1023542、rs2240401、rs10261071、rs12669315、rs6950777、rs2072454、rs2286822、rs733957、rs6957975、rs7779997、rs362726、rs607755、rs2520272、rs213950、rs3815221、rs3779032、rs7830、rs3802100、rs1550697、rs3020221、rs2073574、rs12675283、rs2272730、rs2737335、rs7842714、rs3098659、rs6511、rs10093032、rs2261147、rs2069568、rs2272653、rs11780911、rs3817681、rs17855765、rs4244610、rs4251691、rs12683181、rs11243704、rs12358961、rs10828545、rs10491056、rs3817419、rs3740232、rs2435352、rs7089209、rs3812658、rs2105702、rs3750863、rs3758626、rs10999338、rs780668、rs7917781、rs4747203、rs2131956、rs7074064、rs1903858、rs1409332、rs10786229、rs3740486、rs813944、rs196294、rs2278202、rs2272599、rs7942159、rs3758680、rs1799937、rs11037882、rs3740878、rs3729802、rs589691、rs630394、rs736894、rs11604536、rs1109977、rs883223、rs2196168、rs641936、rs1784424、rs591058、rs10895417、rs693147、rs2276424、rs1954787、rs2241501、rs880054、rs10848683、rs2267549、rs216868、rs12426675、rs2518144、rs3759236、rs10772008、rs7955902、rs2276456、rs1034762、rs3803184、rs4075913、rs2071218、rs706815、rs2270267、rs7397862、rs2302629、rs6606734、rs2464195、rs3741591、rs2075784、rs9564692、rs3752451、rs9534342、rs2296533、rs6313、rs9518061、rs661585、rs589985、rs482757、rs3803236、rs2281974、rs178642、rs2073349、rs1152590、rs229581、rs3759753、rs2075179、rs12432149、rs3742656、rs3751582、rs1800419、rs1800404、rs173224、rs422388、rs2279580、rs1801376、rs140605、rs2306187、rs58156069、rs1147129、rs762551、rs1370275、rs9806604、rs2307438、rs9672296、rs3815003、rs2272037、rs7496614、rs224204、rs1641010、rs2280764、rs3115446、rs215901、rs2072061、rs249954、rs7203525、rs243834、rs2304483、rs1532625、rs11076207、rs483053、rs3991715、rs2548861、rs12918876、rs3803679、rs3752827、rs238238、rs12453262、rs17671352、rs1565817、rs2304908、rs876660、rs3744586、rs1736219、rs548973、rs2952976、rs9894648、rs3110641、rs8067890、rs8176161、rs850730、rs2289677、rs2258689、rs3809863、rs2256835、rs3744093、rs758596、rs4342、rs4362、rs3744024、rs11077379、rs3816256、rs3213926、rs7232329、rs3748422、rs8097342、rs2510344、rs12960081、rs1058396、rs1450425、rs1788027、rs2298712、rs1893788、rs6567271、rs1629038、rs3764640、rs2277984、rs2860178、rs620744、rs539887、rs8104339、rs2114724、rs280520、rs3826803、rs2075021、rs2738447、rs6413504、rs2304154、rs8113582、rs1043996、rs2302603、rs10424582、rs55742440、rs1469699、rs3745859、rs10880、rs2246095、rs1799783、rs392891、rs20580、rs3730849、rs2387588、rs4002462、rs1062798、rs12981413、rs3745405、rs269950、rs3729836、rs2076653、rs2073193、rs2281575、rs3803953、rs2295435、rs2295179、rs363050、rs2273060、rs2273061、rs143383、rs2072792、rs4608591、rs2425906、rs6021437、rs2234487、rs3746657、rs6062700、rs41309367、rs2073421、rs2073425、rs8130564、rs872331、rs754507、rs62215498、rs2839077、rs7283989、rs2236486、rs7279347、rs7279622、rs9982233、rs2839226、rs2839257、rs112544、rs2072708、rs2235324、rs5756516、rs1135360、rs743616、rs6639398、rs5980274、rs1458178、rs5986751、rs9781645、rs2209420、rs5984589、rs2808742、rs5917032、rs6529455、rs5931302、rs6643690、rs1781104、rs1781116、rs318173、rs4825889、rs933315、rs1991961、rs1937193、rs652、rs5964206、rs149910、rs1299087、rs5920670、rs6631828、rs973212、rs5933388、rs6649211、rs5916197、rs4898214、rs2071182、rs4826645、rs35284970、rs13447361、rs2267801、rs9786139、rs2075181、rs17316007、rs17269396、rs8179021、rs16980601、rs9341278、rs917759、rs17269816、rs17316543、rs17316592、rs17269928、rs17276358、rs16980641、rs11096432、rs9786502、rs2032652、rs16980426、rs13447443、rs17323322、rs13447354、rs2033003、rs16980610、rs3848982、rs2075640、rs16980711、rs9786707、rs17276345、rs9786479、rs9306845、rs11096433、rs52812045、rs4589047、rs17250121、rs2032650。

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权利要求：

百度查询： 复旦大学 一种用于亲子鉴定的SNP位点组合、及其检测引物对和应用